I'm having the same problem. The Full HTML response looks like this:
Internal Server Error
There was an internal server error.
The error has been logged with log identifier 424578310.
Please provide this log identifier to technical support.
EDIT:
So, it looks like this problem goes away if I make a '/login' request with my client prior to trying to get contacts, campaigns, etc. Not a very descriptive error message but at least it works now.